Mechanistic Virology: Where Structure Meets Function The geometric principles underpinning virus structure provide a key to uncovering the mechanisms by which viruses replicate and infect their hosts. Combining purpose-designed geometric and topological descriptors of virus architecture with biophysical modelling and experiment reveals how viral geometry impacts on function at different stages of a viral life cycle. These mechanistic insights enable novel solutions to open problems in virus nanotechnology and antiviral therapy. This article was published on 2025-04-22
